Stark Lion's Mane 500 mg 60 tablets (lion's mane, cognitive support)

Stark Lion's Mane 500 mg 60 tablets — support for cognitive activity and the nervous system

Stark Lion's Mane is a Stark Pharm food supplement based on the extract of the fruiting body of the ericaceous bramble (lion's mane, Hericium erinaceus).

The product is designed for daily diet when clarity of thinking, concentration and memory support are important, as well as comfort of the nervous system during periods of stress.

The tablet form is convenient for accurate dosing and regular course intake.

Briefly about the product:

• Blackthorn fruit body extract 50% — 500 mg in 1 tablet
• Polysaccharides — 250 mg in 1 tablet
• Serving size: 1 tablet
• Release form: tablets
• Packaging: 60 tablets
• Permissible deviation of component mass per tablet ±10%

How it works:

• Cognitive support: may help maintain mental clarity and focus.
• Nervous system: may help maintain normal nervous system function.
• Performance: Can help maintain productivity during stressful periods.
• Emotional balance: can contribute to a more peaceful state of mind amid daily stresses.
• Immune support: may help support the body's natural defenses.
• Digestive comfort: may be appropriate as part of a diet to support overall gastrointestinal health.

The effect of the Stark Lion's Mane supplement

• Memory: May help maintain memory and learning processes.
• Attention: may help maintain concentration and focus.
• Nervous system: may help maintain the functional state of the nervous system.
• Performance: may help maintain performance during active periods.
• Stress resilience: can help maintain a more balanced response to stressors.
• Immunity: May help support the immune system as part of a balanced diet.
• Metabolic processes: may help maintain normal metabolic processes.

Lion's Mane mechanism of action “in a chain” (molecule → receptor/signal → effect)

By “biomechanics” here it is logical to understand the biochemical and neurobiological path : what exactly from the fungus reaches the body, where it “clings”, which cascades it turns on and what it potentially changes. An important nuance: in humans, some of the effects have been confirmed only partially, and many mechanisms are best described in cellular/animal models .

1) Polysaccharides (often β-glucans) → intestinal immunity → systemic signals

• What gets in: large polysaccharides are almost not “absorbed” as a whole molecule, but actively interact with the intestinal mucosa.
• Where they “cling”: to innate immunity receptors on mucosal cells (conditionally: PRR receptors on macrophages/dendritic cells).
• What is activated: signaling cascades (such as NF-κB/others) → the profile of local mediators changes.
• What this gives: potentially less “background” inflammatory stress and better “immune readiness.” Indirectly, this may also be reflected in well-being/fatigue, because inflammatory mediators affect the brain and energy.

2) Bioactive low molecular weight compounds → neurotrophins (NGF/BDNF) → neuronal plasticity

• What you get: Lion's Mane describes compounds like hericenones (most common in the fruiting body) and erinacins (most common in the mycelium). Important: in a fruiting body product, the “weight” usually goes to polysaccharides, not erinacins.
• Key idea: In experimental models, these compounds are associated with increased neurotrophin (NGF/BDNF) expression/signaling in neurons/glia.
• How NGF/BDNF works:
  • NGF binds to the TrkA receptor → the PI3K/Akt (cell survival) and MAPK/ERK (growth of processes, “repair/adaptation”) cascades are activated.
  • BDNF binds to TrkB → enhances synaptic plasticity (conditionally: it is easier for the brain to “adjust connections” to learning/load).
• What it gives in terms of sensations: theoretically - support for memory, learning speed, resistance to mental fatigue , but in people it depends on the dose, duration, initial state and quality of the extract.

3) Oxidative stress → Nrf2/antioxidant enzymes → “environmental protection” for neurons

• Problem: The brain is sensitive to oxidative stress (high oxygen consumption, lots of lipids in the membranes).
• What is described in the models: Lion's Mane components can enhance the Nrf2 pathway → the synthesis of its own antioxidant enzymes (SOD, catalase, GPx) increases.
• Result: potentially less “noise” from free radicals → better conditions for neuronal function and recovery.

4) Gut-brain axis → microbiome/SCFA → neuroinflammation/mood

• Polysaccharides as “food” for the microbiome: some work as a prebiotic substrate → the microbiome produces short-chain fatty acids (e.g., butyrate).
• What butyrate does: affects the gut barrier, immune cells, and neuroinflammation; may also indirectly affect mood/stress reactivity via neurotransmitters and the vagus.

Practical conclusion “in simple words”

• The logic of influence is through the background : nervous tissue (neurotrophins/antioxidant pathways) + immune-intestinal signals (less inflammatory “background”).
• Therefore, the effects, if they appear, are more often expected in a course , and not “immediately after the pill”.

Benefits of the formula

• Standardized extract: 50% with the specified amount of polysaccharides per serving.
• Clear serving: 1 tablet per day as recommended by the manufacturer.
• Convenient format: tablets for regular intake without mixing.
• Course package: 60 tablets for scheduled use.

Who might be interested?

• For people with busy schedules where concentration and mental performance are important
• During periods of intense mental work and study
• For those who want to add lion's mane extract to their daily diet
• During periods of increased stress, when nervous system support and recovery are important

Composition

Composition per 1 tablet: 50% blackthorn fruit body extract (polysaccharides - 250 mg) - 500 mg.

Excipients: lactose.

Recommendations for use: can be recommended as a dietary supplement. Helps reduce nervousness, increase performance. The product should be used as recommended by a trainer or as prescribed by a doctor.

Directions: Adults: 1 serving (1 tablet) per day. Take after meals with a glass of water.

Contraindications: individual sensitivity to the product components, children, pregnant women and during lactation.

Caution: Do not exceed recommended amount. Do not use with any medications without first consulting a doctor.

Release form: tablets.

Packaging: polymer jars of 60 tablets.

Storage conditions: in a dry, sun-protected place at a temperature of 5°C to 25°C and a relative humidity of no more than 75%; out of the reach of children.

Shelf life: 24 months from the date of manufacture (see the label (packaging) for the date of manufacture or "Use by" date).

It is not a medicine.

You can buy Stark Lion's Mane 500 mg 60 tablets Stark Pharm in Kyiv and Ukraine on the websites of our partners and dealers. For current addresses of representatives, stores and online stores, see the "Where to buy?" section.